COMPREHENSIVE PHYLO-GENETIC ANALYSIS OF –PEX11 GENE FAMILY IN Oryza sativa
JAVERIA UMBER *
Government College University Faisalabad (GCUF), Pakistan.
. GULFAM
National Institute for Biotechnology and Genetic Engineering, Pakistan.
URWA MAQSOD
Government College University Faisalabad (GCUF), Pakistan.
ANUSHA LIAQAT
National Institute for Biotechnology and Genetic Engineering, Pakistan.
ZERMINA KHATTAK
Government College University Lahore, Pakistan.
*Author to whom correspondence should be addressed.
Abstract
Peroxin gene 11 has been revealed to have important functions involving photorespiration, beta degradation and peroxisomes biogenesis. In this study we show 5 assumed genes present in Oryza sativa gnome PEX11(1-5) and each contains one conserved motif. The PEX11 sequence from Oryza sativa and other species are divided into three major categories. Despite of its important functions a very limited knowledge is known about PEX11 gene family in rice. This study confirms the five different PEX11 genes in rice and each gene contains one particular conserved domain. Among other members PEX11-2 and PEX11-3 are more closely related and shows recent duplications. Different analysis was done in this study to better understand the structure and phylo-genetic relations of PEX11 genes and its evolutionary analysis. Our results showed that PEX11 genes have conserved domains but have diversification not only in sequences but also in functions.
Keywords: PEX11 gene, phylogenetic analysis, Oryza sativa, evolutionary analysis, peroxisome biogenesis
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References
Crookes WJ, Olsen LJ. Peroxin puzzles and folded freight: Peroxisomal protein import in review. Naturwissenschaften. 1999;86(2):51-61.
Nayidu NK, et al. Comprehensive sequence and expression profile analysis of PEX11 gene family in rice. Gene. 2008;412(1-2): 59-70.
Schrader M, et al. Proliferation and fission of peroxisomes — An update. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2016;1863(5):971-983.
Lazarow PB, Fujiki Y. Biogenesis of peroxisomes. Annual Review of Cell Biology. 1985;1(1):489-530.
Saleem RA, Smith JJ, Aitchison JD. Proteomics of the peroxisome. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2006;1763(12):1541-1551.
Eberhart T, Kovacs WJ. Pexophagy in yeast and mammals: An update on mysteries. Histochemistry and Cell Biology. 2018;150(5): 473-488.
Shai N, Schuldiner M, Zalckvar E. No peroxisome is an island — Peroxisome contact sites. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 2016;1863(5):1061-1069.
Effelsberg D, et al. Pex9p is a new yeast peroxisomal import receptor for PTS1-containing proteins. Journal of Cell Science. 2016;129(21):4057.
Yifrach E, et al. Characterization of proteome dynamics during growth in oleate reveals a new peroxisome-targeting receptor. Journal of Cell Science. 2016;129(21):4067.
Fagarasanu A, Fagarasanu M, Rachubinski RA. Maintaining peroxisome populations: A story of division and inheritance. Annual Review of Cell and Developmental Biology. 2007;23(1): 321-344.
Schlüter A, et al. The evolutionary origin of peroxisomes: An er-peroxisome connection. Molecular Biology and Evolution. 2006;23(4): 838-845.
Gabaldón T, et al. Origin and evolution of the peroxisomal proteome. Biology Direct. 2006; 1(1):8.
Duhita N, et al. The origin of peroxisomes: The possibility of an actinobacterial symbiosis. Gene. 2010;450(1):18-24.
Gabaldón T, Capella-Gutiérrez S. Lack of phylogenetic support for a supposed actinobacterial origin of peroxisomes. Gene. 2010;465(1):61-65.
Mano S, et al. Distribution and characterization of peroxisomes in arabidopsis by visualization with gfp: dynamic morphology and actin-dependent movement. Plant and Cell Physiology. 2002;43(3):331-341.
Hu J. Plant peroxisome multiplication: highly regulated and still enigmatic. Journal of Integrative Plant Biology. 2007;49(8):1112-1118.
Del Río LA, et al. Reactive oxygen species and reactive nitrogen species in peroxisomes. Production, Scavenging, and Role in Cell Signaling. Plant Physiology. 2006;141(2):330-335.
McCartney AW, et al. Localization of the tomato bushy stunt virus replication protein p33 reveals a peroxisome-to-endoplasmic reticulum sorting pathway. The Plant Cell. 2005;17(12):3513-3531.
Lipka V, Panstruga R. Dynamic cellular responses in plant–microbe interactions. Current Opinion in Plant Biology. 2005;8(6): 625-631.
Erdmann R, Blobel G. Giant peroxisomes in oleic acid-induced Saccharomyces cerevisiae lacking the peroxisomal membrane protein Pmp27p. Journal of Cell Biology. 1995; 128(4):509-523.
Passreiter M, et al. Peroxisome biogenesis: Involvement of ARF and coatomer. Journal of Cell Biology. 1998;141(2):373-383.
Voncken JW, et al. Rnf2 (Ring1b) deficiency causes gastrulation arrest and cell cycle inhibition. Proceedings of the National Academy of Sciences of the United States of America. 2003;100(5):2468-2473.
Marshall ES, et al. Prognostic significance of ST-segment depression during adenosine perfusion imaging. American Heart Journal. 1995;130(1):58-66.
Thoms S, Erdmann R. Dynamin‐related proteins and Pex11 proteins in peroxisome division and proliferation. The FEBS Journal. 2005;272(20):5169-5181.