Chemical Composition and Antifungal Activity of Tornabea scutellifera (With.) J. R. Laundon against the Human Pathogenic Fungi Scopulariopsis brevicaulis (Sacc.) Bainier, 1907
Zeinab Barakat *
Department of Botany, Faculty of Sciences, Tishreen University, Lattakia, Syria.
Nawal Ali
Department of Botany, Faculty of Sciences, Tishreen University, Lattakia, Syria.
Naseem Zreek
Department of Botany, Faculty of Sciences, Tishreen University, Lattakia, Syria.
*Author to whom correspondence should be addressed.
Abstract
The aim of this study was to examine the antifungal effects of the lichen (Tornabea scutellifera) different concentrations of extracts (Ethanole.Methanole and Ethylacetate) by using the poisoned food method, against pathogenic fungus (Scopulariopsis brevicaulis). The concentration of 10 mg/ml had the best activity for all of extracts, Ethanolic extract of T. scutellifera showed the best efficacy with (91.66%)followed by Ethylacetate extract with (88.19%) and Methanolic extract with (87.73%).
-The major components of the lichen were identified by using Gas Chromatography-Mass Spectrometry analysis (GC-MS).
Result showed presence of Hexadecanoic acid, Oleic acid, Hexadecanoic acid, methyl ester, and many other compounds some of these components have antifungal activity. We recommend from this study to conduct subsequent studies in the future to isolate and purify the most important biologically active compounds and apply them to experimental animals (In vivo).
Keywords: Tornabea scutellifera, extracts, antifungal activity, GC-MS, hexadecanoic acid