A Comparative Study on Antibacterial Potentiality of Ruellia tuberosa and Andrographis paniculata Extracts from Medicinal Garden of St. Ann’s Campus, Visakhapatnam, India
Prasanthi. Ch *
Department of Microbiology, St. Ann’s Degree College for Women, Malkapuram, Visakhapatnam, Andhra Pradesh, India.
G. Adi Seshu
Department of Botany, St. Ann’s Degree College for Women, Malkapuram, Visakhapatnam, Andhra Pradesh, India.
Sr. Prema Kumari
Department of Botany, St. Ann’s Degree College for Women, Malkapuram, Visakhapatnam, Andhra Pradesh, India.
K. Yatheesha Devi
Department of Botany, St. Ann’s Degree College for Women, Malkapuram, Visakhapatnam, Andhra Pradesh, India.
R. Swapna Swaroopa
Department of Botany, St. Ann’s Degree College for Women, Malkapuram, Visakhapatnam, Andhra Pradesh, India.
*Author to whom correspondence should be addressed.
Abstract
The increasing prevalence of antibiotic-resistant bacterial infections has intensified the search for alternative therapeutic agents from natural sources. This study investigates the phytochemical composition and antimicrobial activity of Ruellia tuberosa and Andrographis paniculate, two medicinal plants known for their therapeutic properties. Phytochemical screening from both plants was performed using standard tests to identify the presence of bioactive compounds. Both plants exhibited significant antibacterial activity. E. coli growth are mostly inhibited than S. aureus and K. pneumoniae The antibacterial potentiality of all three solvent extracts shown against Gram positive and Gram negative bacterial cells. while Andrographis showed broader-spectrum activity, particularly against positive both negative bacterial strains when compared with Ruellia tuberosa.
Keywords: Andrographis paniculata, Ruellia tuberosa, phytochemical analysis, bioactive compounds, antibacterial activity